NUTRITIONAL & DIETARY
Please check back for more FAQs about NUTRITIONAL & DIETARY SUPPLEMENTS
or submit a question via the CONTACT page
Frequently asked questions
You and others frequently call sulforaphane an indirect antioxidant. What does that mean?
Are there good sulforaphane supplements and bad ones?
Absolutely! However, we have only tested a small fraction of the hundreds of supplements that represent themselves as containing meaningful amounts of sulforaphane or sulforaphane-producing compounds — SF, GR, GR + myrosinase, broccoli, broccoli sprouts, or broccoli seeds. Remember that GR (glucoraphanin) plus active myrosinase (an enzyme) produces SF (sulforaphane).
Can you recommend any particular brand of supplements containing either SF, GR, or GR + Myrosinase?
This is a somewhat difficult question to answer. The supplements that we have used in clinical studies and recommended to fellow investigators are: Avmacol (Nutramax Laboratories, containing GR + myrosinase) and Crucera-SGS (Thorne Research, containing GR alone). These, and other high quality supplements use TrueBroc® as a source of GR. I trust and endorse TrueBroc® since it is made, by the company I co-founded almost 25 years ago and have been consulting for since my retirement from JHU. Furthermore, I have personally tested it, and supervised its repeated 3rd party laboratory testing.
We started using supplements in our clinical studies a number of years ago precisely because there are now some good, consistent, and safe supplements on the market. Consistency is really crucial as studies need to be carried out on quality products that deliver standardized amounts of key ingredients with minimal batch-to-batch variability. This is a standard that we, as an academic laboratory, could not hope to maintain forever, but it is something that diligent and conscientious supplement producers can readily accomplish.
Remember that broccoli itself is highly variable with respect to the concentration of these plant compounds, so just seeing products that say they contain broccoli does not mean that they have active ingredients, nor does it indicate how much they contain or guarantee that to the consumer. This is a problem that has plagued the supplement industry for some time now.
We have analyzed many supplements over the years, and there are some very poor supplements. Many of them are terrible in that they do not contain what they say they contain, they contain far less, or even only trace amounts, or they contain materials that are not even broccoli or related to it.